The saving of the umbilical cord blood and the cryopreservation
of the stem cells that are abundant in the cord blood represents
one of the greatest recycling programs in the history of
mankind. In the past, the umbilical cord blood and placenta
blood was considered medical waste and disposed of after
the birth of a newborn. Today, the umbilical cord blood
is considered a life saving source of stem cells that are
a 100 percent biological match to the newborn. In addition,
the collection of the cord blood offers absolutely no risk
to either the mother or to the newborn.
"Don't throw it away" is an
ICBS slogan that was coined by one of the ICBS founders,
Curtis L. Cetrulo, M.D.
and refers to the choices that couples have when deciding
what to do with this valuable resource. The choices include:
discarding the cord blood, donating the specimen to a public
cord blood bank to help someone in need of a stem cell transplant,
or banking the specimen with a private cord blood bank for
the child that has just been born or for his/her family.
Discarding the cord blood at the time of birth as is commonly
done in 99 percent of all deliveries doesn't make any sense
whatsoever. Each year approximately 9000 patients are diagnosed
with diseases that can be treated with stem cells and nearly
70 percent of those in need of a stem cell transplant are
unable to find a match. Often times even if a match can be
located through a bone marrow donor it is after many months,
and the disease has progressed to a point of no return. For
these reasons alone discarding the cord blood does not make
any sense when so many people could benefit from the cells
that are thrown away.
The choice to donate the cord blood to
a public bank seems like a logical solution to the problem
of a lack of HLA matches
but the option of donating a cord blood to a public bank
has been problematic for many years. This past year however,
the US government passed the Stem Cell Therapeutic and research
Act of 2005. This landmark bill provides over $79 million
dollars to public cord blood banks and reauthorizes the National
Marrow Donor Program to act as the coordinating center for
patients that search for cord blood units to provide stem
cells for a transplant. As a result there are now many more
opportunities for pregnant women to donate their child cord
blood. For more information please click on the “Public
Banking” Link.
The third option to save the cord blood
with a private bank makes a lot of sense for individual
families especially if
the medical history of the family includes a disease treatable
by stem cell transplantation. This option is also a good
idea for families without a history of diseases treatable
at this time because the cells that are saved are the newborn's
actual cells. In addition, research on umbilical cord blood
stem cells are proving that these cells have the capability
if placed in the right environment to develop into stem cells
from all systems of the human body. So if you can afford
the cost to privately bank, the ICBS highly recommends that
you do so with a private bank. For more information please
click on the “Private Banking” Link.
In summary, there are approximately 4 million births each
year in the United States. Each birth represents the one
and only chance to collect the umbilical cord blood stem
cells that could cure many diseases including leukemia. Stem
cells, present in umbilical cord blood and placenta blood
have been a source of cells for umbilical cold blood transplantation
(UCBT) since the first case was reported in 1989 in the New
England Journal of Medicine in a patient with Fanconi's anemia.
Since that time over 10,000 patients had received cord blood
transplants, and today over 70 diseases can be treated with
cord blood transplantation.
Some of the diseases for which stem cells can be used for
treatment have been compiled by the National Marrow Donor
Program: www.marrow.org
If a family has a positive history for one of the disorders
listed on the disease list, then the cord blood should definitely
be saved. It is incumbent on physicians, especially obstetricians
and pediatricians to alert patients of the possible use of
stem cells from the umbilical cord/placenta to potentially
treat siblings or other family members.
- International Cord Blood Society. |