The saving of the umbilical
cord blood and the cryopreservation of the stem cells that
are abundant in the cord blood represents one of the greatest
recycling programs in the history of mankind. In the past,
the umbilical cord blood and placenta blood was considered
medical waste and disposed of after the birth of a newborn.
Today, the umbilical cord blood is considered a life saving
source of stem cells that are a 100 percent biological match
to the newborn. In addition, the collection of the cord blood
offers absolutely no risk to either the mother or to the
newborn.
"Don't throw it away" is an ICBS
slogan that was coined by one of the ICBS founders, Curtis
L. Cetrulo, M.D. and refers to the choices that couples have
when deciding what to do with this valuable resource. The
choices include: discarding the cord blood, donating the
specimen to a public
cord blood bank to help someone in need
of a stem cell transplant, or banking the specimen with a
private cord blood bank for the child that has just been
born or for his/her family.
Discarding the cord blood at the time of birth
as is commonly done in 99 percent of all deliveries doesn't
make any sense whatsoever. Each year approximately 9000 patients
are diagnosed with diseases that can be treated with stem
cells and nearly 70 percent of those in need of a stem cell
transplant are unable to find a match.
Often times even if
a match can be located through a bone marrow donor it is
after many months, and the disease has progressed to a
point of no return. For these reasons alone discarding the
cord
blood does not make any sense when so many people could
benefit from the cells that are thrown away.
The choice to donate the cord blood to a public
bank seems like a logical solution to the problem of a lack
of HLA matches but the option of donating a cord blood to
a public bank has been problematic for many years. This past
year however, the US government passed the Stem
Cell Therapeutic and research Act of 2005. This landmark bill provides over
$79 million dollars to public cord blood banks and reauthorizes
the National Marrow Donor Program to act as the coordinating
center for patients that search for cord blood units to provide
stem cells for a transplant. As a result there are now many
more opportunities for pregnant women to donate their child
cord blood. For more information please click on the “Public
Banking” Link.
The third option to save the cord blood with
a private bank makes a lot of sense for individual families
especially if the medical history of the family includes
a disease treatable by stem cell transplantation. This option
is also a good idea for families without a history of diseases
treatable at this time because the cells that are saved are
the newborn's actual cells. In addition, research on umbilical
cord blood stem cells are proving that these cells have the
capability if placed in the right environment to develop
into stem cells from all systems of the human body. So if
you can afford the cost to privately bank, the ICBS highly
recommends that you do so with a private bank. For more information
please click on the “Private
Banking” Link.
In summary, there are approximately 4 million
births each year in the United States. Each birth represents
the one and only chance to collect the umbilical cord blood
stem cells that could cure many diseases including leukemia.
Stem cells, present in umbilical cord blood and placenta
blood have been a source of cells for umbilical cold blood
transplantation (UCBT) since the first case was reported
in 1989 in the New England Journal of Medicine in a patient
with Fanconi's anemia. Since that time over 10,000 patients
had received cord blood transplants, and today over 70 diseases
can be treated with cord blood transplantation.
Some of the diseases for which stem cells can
be used for treatment have been compiled by the National
Marrow Donor Program: www.marrow.org
If a family has a
positive history for one of the disorders listed on the disease
list, then the cord
blood should definitely be saved. It is incumbent on physicians,especially
obstetricians and pediatricians to alert patients of the
possible use of stem cells from
the umbilical cord/placenta
to potentially treat siblings or other family members.
- International Cord Blood Society
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